Brief Contents:

ch 1 Introduction to Cell Signaling
ch 2 Principles and Mechanisms of Protein Interactions
ch 3 Signaling Enzymes and their Allosteric Regulation
ch 4 Role of Post-Translational Modifications in Signaling
ch 5 Subcellular Localization of Signaling Molecules
ch 6 Second Messengers: Small Signaling Mediators
ch 7 Membranes, Lipids, and Enzymes that Modify Them
ch 8 Information Transfer Across the Membrane
ch 9 Regulated Protein Degradation
ch10 The Modular Architecture and Evolution of Signaling Proteins
ch11 Information Processing by Signaling Devices and Networks
ch12 How Cells Make Decisions
ch13 Methods for Studying Signaling Proteins and Networks